순번 | 임상시험 제목 | 적응증 | 연구설계 | 의뢰자/실시기관 | 임상단계 | NCT No | 개시일자 |
---|---|---|---|---|---|---|---|
1 | Study of 2 Medicines (Aztreonam and Avibactam) Compared to Best Available Therapy for Serious Gram-negative Infections | Gram-negative Bacterial Infections | Drug: ATM-AVI|Drug: BAT | Pfizer | Phase 2 | NCT05639647 | 2023-04-18 |
2 | A Study of Nemtabrutinib vs Chemoimmunotherapy for Participants With Previously Untreated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) Without TP53 Aberrations (MK-1026-008, BELLWAVE-008) | Chronic Lymphocytic Leukemia|Small Lymphocytic Leukemia | Drug: Nemtabrutinib|Drug: Fludarabine|Drug: Cyclophosphamide|Drug: Bendamustine|Biological: Rituximab|Biological: Truxima|Biological: Ruxience|Biological: Riabni | Merck Sharp & Dohme LLC | Phase 3 | NCT05624554 | 2023-03-16 |
3 | A Study to Evaluate Change in Disease Activity of Subcutaneous (SC) Epcoritamab Combined With Intravenous and Oral Rituximab, Cyclophosphamide, Doxorubicin Hydrochloride, Vincristine, and Prednisone (R-CHOP) or R-CHOP in Adult Participants With Newly Diagnosed Diffuse Large B-Cell Lymphoma (DLBCL) | Diffuse Large B-Cell Lymphoma | Drug: Epcoritamab|Drug: Cyclophosphamide|Drug: Rituximab|Drug: Vincristine|Drug: Doxorubicin|Drug: Prednisone | AbbVie|Genmab | Phase 3 | NCT05578976 | 2023-02-08 |
4 | Study of Pembrolizumab (MK-3475) Monotherapy Versus Sacituzumab Govitecan in Combination With Pembrolizumab for Participants With Metastatic Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥0% (MK-3475-D46) | Carcinoma, Non-Small-Cell Lung | Biological: Sacituzumab Govitecan|Biological: Pembrolizumab | Merck Sharp & Dohme LLC|Gilead Sciences | Phase 3 | NCT05609968 | 2023-02-06 |
5 | A Clinical Trial of Study Medicine (Marstacimab) in Pediatric Patients With Hemophilia A or Hemophilia B | Hemophilia A|Hemophilia B | Drug: marstacimab | Pfizer | Phase 3 | NCT05611801 | 2022-12-09 |
6 | A Study to Determine the Efficacy and Safety of Luspatercept in Adult Participants With Alpha (α)-Thalassemia | Anemia | Biological: Luspatercept|Drug: Placebo|Other: Best Supportive Care | Bristol-Myers Squibb | Phase 2 | NCT05664737 | 2022-12-09 |
7 | A Study to Evaluate Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Adolescent and Adult Participants With Moderate to Severe Atopic Dermatitis | Atopic Dermatitis | Drug: Upadacitinib|Drug: Dupilumab | AbbVie | Phase 3 | NCT05601882 | 2022-11-28 |
8 | A Study to Assess Disease Activity of Intravenously (IV) Infused Telisotuzumab Vedotin in Adult Participants With Advanced/Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC) | Non Small Cell Lung Cancer | Biological: Telisotuzumab Vedotin | AbbVie | Phase 2 | NCT05513703 | 2022-11-21 |
9 | Safety and Immunogenicity of V116 in Pneumococcal Vaccine-naïve Adults 50 Years of Age or Older (V116-010, STRIDE-10) | Pneumococcal Disease | Biological: V116|Biological: PPSV23 | Merck Sharp & Dohme LLC | Phase 3 | NCT05569954 | 2022-11-07 |
10 | A Study of Coformulated Favezelimab/Pembrolizumab (MK-4280A) Versus Physician's Choice Chemotherapy in PD-(L)1-refractory, Relapsed or Refractory Classical Hodgkin Lymphoma (MK-4280A-008) | Hodgkin Lymphoma | Biological: favezelimab/pembrolizumab|Drug: bendamustine|Drug: gemcitabine | Merck Sharp & Dohme LLC | Phase 3 | NCT05508867 | 2022-10-18 |