순번 | 임상시험 제목 | 적응증 | 연구설계 | 의뢰자/실시기관 | 임상단계 | NCT No | 개시일자 |
---|---|---|---|---|---|---|---|
1 | A Study to Evaluate Pembrolizumab (MK-3475) in Participants With Advanced Esophageal Cancer Previously Exposed to Programmed Cell Death 1 Protein (PD-1)/ Programmed Cell Death Ligand 1 (PD-L1) Treatment | Esophageal Squamous Cell Carcinoma | Drug: Paclitaxel|Drug: Irinotecan|Biological: Pembrolizumab|Biological: MK-4830|Drug: Lenvatinib | Merck Sharp & Dohme LLC | Phase 1|Phase 2 | NCT05319730 | 2023-05-05 |
2 | A Study to Investigate the Safety and Tolerability of Intravenous QEQ278 in Patients With Advanced Solid Tumors | Carcinoma, Non-Small-Cell Lung|Carcinoma, Renal Cell|Esophageal Squamous Cell Carcinoma|Squamous Cell Carcinoma of Head and Neck | Biological: QEQ278 | Novartis Pharmaceuticals|Novartis | Phase 1 | NCT05462873 | 2023-04-04 |
3 | Study of Ianalumab Versus Placebo in Addition to First-line Corticosteroids in Primary Immune Thrombocytopenia (ITP) | Primary Immune Thrombocytopenia (ITP) | Biological: Ianalumab|Drug: Placebo|Drug: Corticosteroids | Novartis Pharmaceuticals|Novartis | Phase 3 | NCT05653349 | 2023-03-06 |
4 | Phase 3 Study to Evaluate Two Regimens of Ianalumab on Top of Standard-of-care Therapy in Patients With Systemic Lupus Erythematosus (SIRIUS-SLE 1) | Systemic Lupus Erythematosus | Drug: Ianalumab|Drug: Placebo | Novartis Pharmaceuticals|Novartis | Phase 3 | NCT05639114 | 2023-03-02 |
5 | A Study to Evaluate Change in Disease Activity of Subcutaneous (SC) Epcoritamab Combined With Intravenous and Oral Rituximab, Cyclophosphamide, Doxorubicin Hydrochloride, Vincristine, and Prednisone (R-CHOP) or R-CHOP in Adult Participants With Newly Diagnosed Diffuse Large B-Cell Lymphoma (DLBCL) | Diffuse Large B-Cell Lymphoma | Drug: Epcoritamab|Drug: Cyclophosphamide|Drug: Rituximab|Drug: Vincristine|Drug: Doxorubicin|Drug: Prednisone | AbbVie|Genmab | Phase 3 | NCT05578976 | 2023-02-08 |
6 | A Study of Efficacy and Safety of Ianalumab Versus Placebo in Addition to Eltrombopag in Primary Immune Thrombocytopenia Patients Who Failed Steroids | Primary Immune Thrombocytopenia | Biological: Ianalumab|Drug: Eltrombopag|Drug: Placebo | Novartis Pharmaceuticals|Novartis | Phase 3 | NCT05653219 | 2023-02-02 |
7 | A Study to Evaluate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Anti-tumor Activity of RO7616789 in Advanced Small Cell Lung Cancer and Other Neuroendocrine Carcinomas | Small Cell Lung Cancer|Neuroendocrine Carcinoma | Drug: RO7616789|Drug: Tocilizumab | Hoffmann-La Roche | Phase 1 | NCT05619744 | 2023-01-23 |
8 | Phase IIIb, Open-label, Multi-center Study to Evaluate Safety, Tolerability and Efficacy of OAV101 Administered Intrathecally to Participants With SMA Who Discontinued Treatment With Nusinersen or Risdiplam | Spinal Muscular Atrophy | Genetic: OAV101 | Novartis Pharmaceuticals|Novartis | Phase 3 | NCT05386680 | 2023-01-12 |
9 | Safety and Immunogenicity of V116 in Vaccine-naïve Japanese Older Adults (V116-009, STRIDE-9) | Pneumococcal Disease | Biological: V116|Biological: PPSV23 | Merck Sharp & Dohme LLC | Phase 3 | NCT05633992 | 2023-01-10 |
10 | A Study of Efficacy and Safety of Ianalumab in Previously Treated Patients With Warm Autoimmune Hemolytic Anemia | Warm Autoimmune Hemolytic Anemia (wAIHA) | Biological: Ianalumab|Drug: Placebo | Novartis Pharmaceuticals|Novartis | Phase 3 | NCT05648968 | 2022-12-30 |