외국의 약물유전정보

Trametinib

미국 FDA   원본 보기 | 번역본 보기

6 ADVERSE REACTIONS
6.1 Clinical Trials Experience
 - Unresectable or Metastatic BRAF V600E Mutation Positive Melanoma
The trials excluded patients with abnormal left ventricular ejection fraction, history of acute coronary syndrome within 6 months, history of Class II or greater congestive heart failure (New York Heart Association), history of RVO or PRED, QTcB interval ≥480 msec, uncontrolled hypertension, uncontrolled arrhythmias, active brain metastasese, or known history of G6PD deficiency. 

(2018.4.30 업데이트)